In 2019, we conducted a survey with 169 respondents who are suffering from histamine intolerance and / or mast cell activation syndrome. The results are published below.

Our goal is to make this an ongoing survey, amassing as much data as possible so that people suffering from these conditions can gain some guidance on trends and which treatments people are seeking. We also hope that it can serve as a data point for doctors and practitioners as awareness for histamine disorders is still very low.

If you haven’t already, please fill out the survey and help us make this the largest online data source for histamine intolerance. Information is power and the more data we have, the more likely we are to find a quicker path to recovery and raise awareness on this condition.

The results of the survey will continue to be updated on this site in the hopes that it can provide some value to you and the community of people suffering from histamine intolerance. If you have any suggestions on how to improve the survey, please contact us at

Key Findings

Based on our interpretation of the data, the following key trends were discovered:

  • The overwhelming majority of the respondents are female
  • Most respondents are over the age of 31
  • Most respondents were based in the US and UK
  • Only 35% of respondents have received a formal diagnosis of histamine intolerance and / or mast cell activation syndrome
  • A little over half of the respondents are currently seeing a practitioner for their condition
  • Upon comparing the group of respondents who are seeing a practitioner to those who are not, on average, there was no difference in the extent to which they felt their condition was under control
  • The most common pain points for the respondents were skin and gastrointestinal issues
  • Respondents identified community forums and Facebook groups as the most helpful ongoing resource for their condition. Please see our Note on the Data for reference.
  • In terms of protocol, almost half of all respondents are currently on a low histamine diet, followed by antihistamines, quercetin, and probiotics.
  • The most desired resource for respondents are doctors who have knowledge of these conditions.

A Note on the Data

While surveys are the most common method for data collection, there are always a number of risks when collecting and evaluating the data. The majority of the respondents of this survey for example were obtained from Facebook groups. Therefore any data showing Facebook as a preferred method of communication or knowledge will be skewed positively.


This article is for informational purposes only. It is not meant to diagnose or recommend treatment options for your condition. Always consult a medical practitioner before making any changes to your medication protocol or diet.

The content provided is for informational purposes only and is not intended to medically diagnose or prescribe a solution for your condition.